Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633782 | 1.00 | LMNA (0.37) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL8356828 | 0.76 | ADRB1 (0.38) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL17384668 | 0.75 | TK1 (0.38) | LMNASMN1; SMN2TK1TK2SLC5A2 | |
| SCHEMBL16631950 | 0.74 | TK1 (0.39) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL8927834 | 0.74 | LMNA (0.38) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL27165201 | 0.74 | ADRB1 (0.41) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL9751247 | 0.74 | ADRB1 (0.38) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL8663124 | 0.74 | ADRB1 (0.38) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL8961007 | 0.71 | DNMT1 (0.35) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL8698135 | 0.71 | DNMT1 (0.35) | LMNASMN1; SMN2ADRB1DNMT1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126439-A | Complementary purines and pyrimidines | TEMPLE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0333832-B1 | ARTIFICIAL DNA BASE PAIR ANALOGUES | TEMPLE UNIVERSITY (US) | 1992-06-03 | — | — | EP | disclosed |
| EP-0333832-A1 | ARTIFICIAL DNA BASE PAIR ANALOGUES | TEMPLE UNIVERSITY (US) | 1989-09-27 | — | — | EP | disclosed |
| WO-1989002921-A1 | ARTIFICIAL DNA BASE PAIR ANALOGUES | TEMPLE UNIVERSITY (US) | 1989-04-06 | — | — | WO | disclosed |