Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17374838 | 1.00 | GLO1 (0.41) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL19240026 | 0.86 | GLO1 (0.50) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL18936293 | 0.81 | NPSR1 (0.42) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL18936291 | 0.81 | NPSR1 (0.42) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL16692406 | 0.76 | NPSR1 (0.48) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL364547 | 0.74 | NPSR1 (0.47) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL364548 | 0.74 | NPSR1 (0.47) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL12294394 | 0.73 | GLO1 (0.38) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL962610 | 0.73 | CYP2C9 (0.47) | GLO1NPSR1ALDH1A1GAACYP2D6 | |
| SCHEMBL12081760 | 0.73 | CYP2C9 (0.47) | GLO1NPSR1ALDH1A1GAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10349656-B2 | Difluoromethyl-nicotinic-indanyl carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-16 | — | — | US | disclosed |
| EP-3160941-B1 | DIFLUOROMETHYL-NICOTINIC-INDANYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2019-01-16 | — | — | EP | disclosed |
| US-20170150717-A1 | Difluoromethyl-nicotinic-indanyl carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20170150717-A1 | Difluoromethyl-nicotinic-indanyl carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-01 | — | — | US | disclosed |
| WO-2015197530-A2 | DIFLUOROMETHYL-NICOTINIC-INDANYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170150717-A1 | Difluoromethyl-nicotinic-indanyl carboxamides | NNMT, NAPRT, NAMPT | GLO1 651/4885NPSR1 4192/4885ALDH1A1 2673/4885 |
| US-10349656-B2 | Difluoromethyl-nicotinic-indanyl carboxamides | NNMT, NAPRT, NAMPT | GLO1 651/4885NPSR1 4192/4885ALDH1A1 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.