Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EED | O75530 | 1/20 | 0.30 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15485301 | 0.82 | HTT (0.39) | PDK2ALPIALPGPLAAL3MBTL1 | |
| SCHEMBL12017379 | 0.81 | SMN1; SMN2 (0.38) | ALPIALPGPLAAL3MBTL1AR | |
| SCHEMBL673074 | 0.78 | MAPT (0.42) | PDK2IKBKETBK1ERCC5PIM1 | |
| SCHEMBL17382262 | 0.78 | CCNC (0.43) | PDK2AR | |
| SCHEMBL1140165 | 0.77 | ALDH1A1 (0.49) | PDK2IKBKETBK1KDM4EALDH1A1 | |
| SCHEMBL13102449 | 0.77 | ALPI (0.53) | PDK2IKBKETBK1ALPIALPG | |
| SCHEMBL2748698 | 0.77 | KDM4E (0.39) | ALPIALPGPLAAL3MBTL1AR | |
| SCHEMBL12492720 | 0.77 | CCNC (0.45) | PDK2AURKBALOX5AP | |
| SCHEMBL16876622 | 0.75 | ACHE (0.36) | — | |
| SCHEMBL2554333 | 0.74 | PDK2 (0.37) | PDK2IKBKETBK1ERCC5PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015196335-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | TOCOPHERX, INC. (US) | 2015-12-30 | — | — | WO | disclosed |