SCHEMBL17385243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2238173	0.91	PTGS2 (1.00)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL2600801	0.90	AKR1C3 (1.00)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL15774085	0.90	AKR1C3 (0.83)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL6424077	0.89	PTGS2 (0.77)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL16656482	0.89	AKR1C3 (1.00)	PTGS2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL5554764	0.88	PTGS2 (0.76)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL15215990	0.87	AKR1C3 (0.79)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL16254106	0.87	AKR1C3 (0.78)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL17208137	0.87	AKR1C3 (0.78)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA
	SCHEMBL8645594	0.85	AKR1C3 (1.00)	PTGS2PLA2G2AAKR1C3AKR1C2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.