Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27065040 | 0.98 | LMNA (0.49) | ALDH1A1LMNAKDM4ETSHRTBXAS1 | |
| SCHEMBL13285868 | 0.98 | LMNA (0.49) | ALDH1A1LMNAKDM4ETSHRTBXAS1 | |
| SCHEMBL15132436 | 0.98 | LMNA (0.49) | ALDH1A1LMNAKDM4ETSHRTBXAS1 | |
| Bromide SCHEMBL5075234 | 0.97 | LMNA (0.48) | ALDH1A1LMNAKDM4ETSHRTBXAS1 | |
| Bromide SCHEMBL5074991 | 0.97 | LMNA (0.48) | ALDH1A1LMNAKDM4ETSHRTBXAS1 | |
| SCHEMBL17361242 | 0.95 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4ETSHRTBXAS1 | |
| Bromide SCHEMBL28529432 | 0.93 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ETSHRTBXAS1 | |
| SCHEMBL9524467 | 0.88 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ETSHRESRRB | |
| SCHEMBL8374043 | 0.84 | CYP4F2 (0.52) | ALDH1A1TBXAS1SMN1; SMN2 | |
| SCHEMBL8972407 | 0.83 | MEN1 (0.39) | ALDH1A1LMNAKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015200187-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | Reiley Pharmaceuticals, Inc. (US) | 2015-12-30 | — | — | WO | disclosed |