SCHEMBL8972407

SCHEMBL8972407

O=C(CCCC[PH](c1ccccc1)(c1ccccc1)c1ccccc1)OC(=O)OC(=O)CCCC[PH](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
ALPL P05186 1/20 0.39
ALPI P09923 1/20 0.39
ALPG P10696 1/20 0.39
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.36
PRSS1 P07477 2/20 0.36
CTSG P08311 1/20 0.36
CTRB1 P17538 1/20 0.36
CMA1 P23946 1/20 0.36
LMNA P02545 3/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
POLB P06746 1/20 0.35
BLM P54132 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17385252 0.83 ALDH1A1 (0.50) MEN1KMT2AALPLALPIALPG
SCHEMBL28323948 0.83 MEN1 (0.39) MEN1KMT2AALPLALPIALPG
SCHEMBL15132436 0.82 LMNA (0.49) MEN1KMT2AALPLALPIALPG
SCHEMBL27065040 0.82 LMNA (0.49) MEN1KMT2AALPLALPIALPG
SCHEMBL15455405 0.82 PRSS1 (0.52) MEN1KMT2AALPLALPIALPG
SCHEMBL13285868 0.82 LMNA (0.49) MEN1KMT2AALPLALPIALPG
SCHEMBL8374043 0.81 CYP4F2 (0.52) L3MBTL1ALDH1A1POLBCYP4F2CYP4A11
Bromide SCHEMBL5075234 0.81 LMNA (0.48) MEN1KMT2AALPLALPIALPG
Bromide SCHEMBL5074991 0.81 LMNA (0.48) MEN1KMT2AALPLALPIALPG
SCHEMBL1838985 0.80 HDAC3 (0.50) L3MBTL1ALDH1A1MAPK1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578694-A MELT POLYCONDENSATION OF AROMATIC DIOL AND DIARYL CARBONATE; ESTER INTERCHANGE USING PHOSPHONIUM CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 1996-11-26 US disclosed
EP-0703262-A2 Process for producing aromatic polycarbonate Mitsubishi Chemical Corporation (JP) 1996-03-27 EP disclosed