SCHEMBL29538955

SCHEMBL29538955

CCOC(=O)c1nn(-c2cc(Cl)cc(Cl)c2)c2c1COc1cc(OC)c(Br)cc1-2

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 3/20 0.43
▸ CDK2 P24941 3/20 0.43
▸ CCNA1 P78396 3/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ ALDH1A1 P00352 4/20 0.39
▸ TP53 P04637 3/20 0.38
▸ POLB P06746 1/20 0.38
▸ LMNA P02545 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ NPBWR1 P48145 1/20 0.35
▸ MAPT P10636 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17381607 1.00 CCNA2 (0.43) CCNA2CDK2CCNA1L3MBTL1ALDH1A1
SCHEMBL17385442 0.91 CCNA2 (0.49) CCNA2CDK2CCNA1ALDH1A1TP53
SCHEMBL30885867 0.90 CCNA2 (0.43) CCNA2CDK2CCNA1L3MBTL1ALDH1A1
SCHEMBL17385521 0.90 L3MBTL1 (0.42) CCNA2CDK2CCNA1L3MBTL1ALDH1A1
SCHEMBL30885869 0.88 CCNA2 (0.39) CCNA2CDK2CCNA1L3MBTL1ALDH1A1
SCHEMBL17381608 0.88 CCNA2 (0.39) CCNA2CDK2CCNA1L3MBTL1ALDH1A1
SCHEMBL17385323 0.87 ALDH1A1 (0.51) CCNA2CDK2CCNA1ALDH1A1TP53
SCHEMBL16377773 0.86 CCNA2 (0.43) CCNA2CDK2CCNA1ALDH1A1TP53
SCHEMBL30759600 0.84 CCNA2 (0.47) CCNA2CDK2CCNA1L3MBTL1ALDH1A1
SCHEMBL27119351 0.84 CCNA2 (0.47) CCNA2CDK2CCNA1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 — — EP disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 — — WO disclosed
CN-106573937-B Pyrazole compounds as FSHR modulators and uses thereof 阿瑞斯贸易股份公司 2022-02-11 — — CN disclosed
Send feedback