SCHEMBL17386403

SCHEMBL17386403

CC(N)(CC=Cc1ccccc1)C(=Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.46
PAM P19021 1/20 0.44
AKR1C3 P42330 1/20 0.41
AKR1C1 Q04828 1/20 0.40
MMP1 P03956 1/20 0.39
MMP9 P14780 1/20 0.39
MMP13 P45452 1/20 0.39
NPC1 O15118 1/20 0.39
TSHR P16473 1/20 0.39
EGFR P00533 1/20 0.39
HTR2A P28223 3/20 0.38
MAOB P27338 1/20 0.38
GRIK1 P39086 2/20 0.38
GRIK2 Q13002 2/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8995849 0.83 CYP2C19 (0.57) CYP2C19PAMMMP1MMP9MMP13
SCHEMBL8995848 0.83 CYP2C19 (0.57) CYP2C19PAMMMP1MMP9MMP13
SCHEMBL8995846 0.81 CYP2C19 (0.51) CYP2C19PAMMMP1MMP9MMP13
SCHEMBL525211 0.73 AKR1C3 (0.55) CYP2C19AKR1C3AKR1C1NPC1TSHR
SCHEMBL525210 0.73 AKR1C3 (0.55) CYP2C19AKR1C3AKR1C1NPC1TSHR
SCHEMBL1716940 0.73 PAM (0.53) CYP2C19PAMMMP1MMP9MMP13
SCHEMBL10619280 0.73 PAM (0.53) CYP2C19PAMMMP1MMP9MMP13
SCHEMBL1716939 0.73 PAM (0.53) CYP2C19PAMMMP1MMP9MMP13
SCHEMBL7564687 0.72 AKR1C3 (0.46) CYP2C19AKR1C3AKR1C1NPC1TSHR
SCHEMBL20036796 0.71 TDP1 (0.47) CYP2C19PAMMMP1MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2963066-B1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORP (JP) 2017-12-27 EP disclosed
US-20160009903-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORPORATION (JP) 2016-01-14 US disclosed
EP-2963066-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR Corporation (JP) 2016-01-06 EP disclosed