SCHEMBL1716940

SCHEMBL1716940

CC(C)(CC=Cc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.53
CYP2C19 P33261 1/20 0.51
PPARA Q07869 2/20 0.51
NPC1 O15118 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
EGFR P00533 1/20 0.46
HTR2A P28223 3/20 0.46
GLA P06280 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MMP1 P03956 1/20 0.45
MMP9 P14780 1/20 0.45
MMP13 P45452 1/20 0.45
MAOB P27338 1/20 0.45
HDAC3 O15379 1/20 0.44
TNKS O95271 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1716939 1.00 PAM (0.53) PAMCYP2C19PPARANPC1L3MBTL1
SCHEMBL10619280 0.85 PAM (0.53) PAMCYP2C19PPARANPC1L3MBTL1
SCHEMBL17651664 0.84 LMNA (0.48) CYP2C19PPARALMNASMN1; SMN2
SCHEMBL17651663 0.84 LMNA (0.48) CYP2C19PPARALMNASMN1; SMN2
SCHEMBL27364941 0.83 PAM (0.47) PAMCYP2C19PPARANPC1EGFR
SCHEMBL8995849 0.82 CYP2C19 (0.57) PAMCYP2C19PPARANPC1EGFR
SCHEMBL8995848 0.82 CYP2C19 (0.57) PAMCYP2C19PPARANPC1EGFR
SCHEMBL3141225 0.82 PPARA (0.56) PAMCYP2C19PPARANPC1L3MBTL1
SCHEMBL17651678 0.82 PPARA (0.62) CYP2C19PPARANPC1MMP1MMP9
SCHEMBL16213234 0.82 PPARA (0.62) CYP2C19PPARANPC1MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1967080-B1 Non-aldehyde cinnamon flavor and delivery systems therefor CADBURY ADAMS USA LLC (US) 2010-06-02 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
EP-0428276-B1 Acaricidal composition TAKASAGO PERFUMERY CO LTD (JP) 1998-09-16 EP claimed
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP disclosed
EP-3911172-A1 COMBINATION REMEDY Symrise AG (DE) 2021-11-24 EP disclosed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
WO-2020147977-A1 COMBINATION REMEDY SYMRISE AG (DE) 2020-07-23 WO disclosed
EP-3474833-A1 CINNAMYL ALCOHOL DERIVATIVE FOR REDUCING APPETITE AND FOR GENERATING THE FEELING OF BEING FULL Symrise AG (DE) 2019-05-01 EP disclosed
US-10017441-B2 Direct anti-markovnikov addition of acids to alkenes THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2018-07-10 US disclosed
EP-2145042-B1 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2018-01-17 EP disclosed
WO-2017220168-A1 CINNAMYL ALCOHOL DERIVATIVE FOR REDUCING APPETITE AND FOR GENERATING THE FEELING OF BEING FULL SYMRISE AG (DE) 2017-12-28 WO disclosed
US-20160096791-A1 DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES UNIV NORTH CAROLINA (US) 2016-04-07 US disclosed
EP-2145042-A1 TEXTILE SCENTING Henkel AG & Co. KGaA (DE) 2010-01-20 EP disclosed
WO-2008135306-A1 TEXTILE SCENTING HENKEL AG & CO. KGAA (DE) 2008-11-13 WO disclosed
EP-1928992-A1 CONSUMER PRODUCTS HAVING VARYING ODORS Henkel AG & Co. KGaA (DE) 2008-06-11 EP disclosed
EP-1922398-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-21 EP disclosed
WO-2007028479-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
WO-2007028477-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160096791-A1 DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES HAO2, DUOX2, PDK2 PAM 453/4885CYP2C19 796/4885PPARA 456/4885
US-10017441-B2 Direct anti-markovnikov addition of acids to alkenes HAO2, DUOX2, PDK2 PAM 453/4885CYP2C19 796/4885PPARA 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.