Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995848 | 1.00 | CYP2C19 (0.57) | CYP2C19PAMMAOBNPC1TSHR | |
| SCHEMBL8995846 | 0.88 | CYP2C19 (0.51) | CYP2C19PAMMAOBNPC1TSHR | |
| SCHEMBL29697102 | 0.87 | BLM (0.54) | CYP2C19MAOBEGFRTDP1 | |
| SCHEMBL17386403 | 0.83 | CYP2C19 (0.46) | CYP2C19PAMMAOBNPC1TSHR | |
| SCHEMBL10619280 | 0.82 | PAM (0.53) | CYP2C19PAMMAOBNPC1TSHR | |
| SCHEMBL1716940 | 0.82 | PAM (0.53) | CYP2C19PAMMAOBNPC1TSHR | |
| SCHEMBL1716939 | 0.82 | PAM (0.53) | CYP2C19PAMMAOBNPC1TSHR | |
| Phosphoric Acid SCHEMBL30804542 | 0.82 | BLM (0.49) | CYP2C19MAOBEGFRTDP1 | |
| SCHEMBL6192218 | 0.78 | PAM (0.49) | CYP2C19PAMMAOBNPC1TSHR | |
| SCHEMBL7453582 | 0.77 | CYP2C19 (0.48) | CYP2C19PAMMAOBNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494716-B1 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM NV (NL) | 1996-08-28 | — | — | EP | disclosed |
| US-5248608-A | Enzyme catalyzed stereospecific hdyrolysis | DSM N.V. (NL) | 1993-09-28 | — | — | US | disclosed |
| EP-0494716-A2 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM N.V. (NL) | 1992-07-15 | — | — | EP | disclosed |