Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386528 | 0.96 | HSD11B1 (0.44) | HSD11B1CYP2D6NPY5RSIGMAR1AVPR1A | |
| SCHEMBL3223126 | 0.82 | SIGMAR1 (0.48) | NPY5RSIGMAR1AVPR1A | |
| SCHEMBL350821 | 0.82 | SIGMAR1 (0.48) | NPY5RSIGMAR1AVPR1A | |
| Hydrochloric Acid SCHEMBL349643 | 0.80 | SIGMAR1 (0.47) | NPY5RSIGMAR1AVPR1A | |
| SCHEMBL11829064 | 0.74 | SIGMAR1 (0.51) | NPY5RSIGMAR1AVPR1A | |
| SCHEMBL29674557 | 0.73 | SIGMAR1 (0.54) | NPY5RSIGMAR1AVPR1A | |
| SCHEMBL171980 | 0.73 | SIGMAR1 (0.54) | NPY5RSIGMAR1AVPR1A | |
| Hydrochloric Acid SCHEMBL2002554 | 0.72 | SIGMAR1 (0.52) | NPY5RSIGMAR1AVPR1A | |
| SCHEMBL27594932 | 0.72 | DRD2 (0.55) | HSD11B1CYP2D6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1995606 | 0.71 | SIGMAR1 (0.51) | NPY5RSIGMAR1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963021-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Holdings Corporation (US) | 2016-01-06 | — | — | EP | disclosed |