Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17389150 | 0.93 | ALOX5 (0.61) | ALOX5ELANEPTGS1CYP3A4AKR1C3 | |
| SCHEMBL10827946 | 0.80 | TSHR (0.61) | ALOX5ELANEPTGS1CYP3A4AKR1C3 | |
| SCHEMBL5931917 | 0.80 | ALOX5 (0.75) | ALOX5ELANEPTGS1AKR1C3AKR1C2 | |
| SCHEMBL9490716 | 0.80 | ALOX5 (0.63) | ALOX5ELANEPTGS1AKR1C3AKR1C2 | |
| SCHEMBL7287677 | 0.80 | ALOX5 (0.54) | ALOX5ELANEPTGS1AKR1C3AKR1C2 | |
| SCHEMBL1399489 | 0.79 | ALOX5 (0.55) | ALOX5ELANEPTGS1TDP1MAPT | |
| SCHEMBL31112657 | 0.79 | ALOX5 (0.55) | ALOX5ELANEPTGS1TDP1MAPT | |
| SCHEMBL22031072 | 0.79 | ELANE (0.54) | ALOX5ELANEPTGS1CYP3A4AKR1C3 | |
| Bromide SCHEMBL7277996 | 0.78 | ALOX5 (0.53) | ALOX5ELANEPTGS1TDP1MAPT | |
| SCHEMBL4512063 | 0.77 | ALOX5 (0.50) | ALOX5ELANECYP3A4PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164447-B1 | ESTER-FUNCTIONAL POLYSILOXANES AND COPOLYMERS MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-10-09 | — | — | EP | disclosed |
| US-9957357-B2 | Ester-functional polysiloxanes and copolymers made therefrom | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170066885-A1 | ESTER-FUNCTIONAL POLYSILOXANES AND COPOLYMERS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2017-03-09 | — | — | US | disclosed |
| US-9518182-B2 | Ester-functional polysiloxanes and copolymers made therefrom | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160002410-A1 | ESTER-FUNCTIONAL POLYSILOXANES AND COPOLYMERS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-01-07 | — | — | US | disclosed |