Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578895 | 0.77 | MAOB (0.49) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27625865 | 0.77 | KDM4E (0.42) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL634602 | 0.77 | CCR4 (0.50) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6594750 | 0.77 | CYP2C19 (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL2450078 | 0.75 | KDM4E (0.71) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9341138 | 0.74 | ALDH1A1 (0.62) | KDM4EMEN1KMT2AALDH1A1GAA | |
| Isothiocyanate SCHEMBL27907719 | 0.73 | KDM4E (0.63) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5532851 | 0.73 | KDM4E (0.73) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30153359 | 0.73 | KDM4E (0.73) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19378623 | 0.69 | KDM4E (0.58) | KDM4EMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160000886-A1 | NANOSTRUCTURED ACTIVE THERAPEUTIC VEHICLES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2016-01-07 | — | — | US | disclosed |