SCHEMBL5532851

SCHEMBL5532851

Cc1c(O)c(=O)oc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.73
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
ALDH1A1 P00352 3/20 0.56
NQO1 P15559 3/20 0.56
MEN1 O00255 2/20 0.56
CYP3A4 P08684 2/20 0.56
KMT2A Q03164 2/20 0.56
ABCB11 O95342 1/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.56
CYP2C19 P33261 1/20 0.56
PDE4D Q08499 1/20 0.56
PCSK7 Q16549 1/20 0.56
GPR35 Q9HC97 1/20 0.56
MAPT P10636 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153359 1.00 KDM4E (0.73) KDM4ECA12CA9ALDH1A1NQO1
Isothiocyanate SCHEMBL27907719 0.92 KDM4E (0.63) KDM4ECA12CA9ALDH1A1NQO1
SCHEMBL5459905 0.85 KDM4E (1.00) KDM4ECA12CA9ALDH1A1NQO1
SCHEMBL29695571 0.85 KDM4E (1.00) KDM4ECA12CA9ALDH1A1NQO1
SCHEMBL2450078 0.84 KDM4E (0.71) KDM4ECA12CA9ALDH1A1MEN1
SCHEMBL7737431 0.82 KDM4E (0.69) KDM4ECA12CA9ALDH1A1NQO1
SCHEMBL29872 0.82 KDM4E (0.69) KDM4ECA12CA9ALDH1A1NQO1
SCHEMBL29379994 0.82 KDM4E (0.69) KDM4ECA12CA9ALDH1A1NQO1
Hydrochloric Acid SCHEMBL8701572 0.80 KDM4E (0.67) KDM4ECA12CA9ALDH1A1NQO1
Acetic Acid SCHEMBL15653002 0.79 KDM4E (0.66) KDM4ECA12CA9ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO claimed
CN-109232497-B Coumarin cationic photoinitiator and preparation method thereof 上海予利生物科技股份有限公司 2024-07-16 CN claimed
CN-109342381-A A kind of fluorescent dyeing reagent 广州往圣生物科技有限公司 2019-02-15 CN claimed
CN-109232497-A A kind of Coumarins cation light initiator and preparation method thereof 上海予利生物科技股份有限公司 2019-01-18 CN claimed
CN-103515041-B High thermal stability pellet composition and its preparation method and application for hot stopper 热敏碟公司 2018-11-27 CN claimed
CN-101723925-B Preparation method of 7-hydroxy-4-methylcoumarin ZHOU CHENGYUN (CN) 2012-02-01 CN claimed
CN-101723925-A Preparation method of 7-hydroxy-4-methylcoumarin CHENGYUN ZHOU 2010-06-09 CN claimed
US-20250353855-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE PTC THERAPEUTICS INC (US) 2025-11-20 US disclosed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO disclosed
CN-109232497-B Coumarin cationic photoinitiator and preparation method thereof 上海予利生物科技股份有限公司 2024-07-16 CN disclosed
CN-110950851-B Triazinyl coumarin type fluorescent whitening agent and preparation method and application thereof 营口理工学院 2023-03-21 CN disclosed
CN-111491524-A Preparation method of Aloe powder 森永乳业株式会社 2020-08-04 CN disclosed
CN-110950851-A Triazinyl coumarin type fluorescent whitening agent and preparation method and application thereof 营口理工学院 2020-04-03 CN disclosed
CN-102344501-A Preparation method of coumarin-modified hyaluronic acid graft micelle emulsifier UNIV JIANGNAN 2012-02-08 CN disclosed
CN-101932925-A Methods and systems for removing autofluorescence from images GEN ELECTRIC 2010-12-29 CN disclosed
US-7227158-B1 Stick-on self-indicating instant radiation dosimeter JP LABS, INC. (US) 2007-06-05 US disclosed
US-6740526-B1 Quantitative transient protein expression in plant tissue culture PENN STATE RESEARCH FOUNDATION, THE 2004-05-25 US disclosed
CN-1125467-A Process for screening substances having a modulating effect on an interleukine-5-receptor-dependent cellular signal transmission path BOEHRINGER INGELHEIM INT (DE) 1996-06-26 CN disclosed
EP-0387715-A2 Electroluminescent element IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353855-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE HTT, HYPK, FH KDM4E 3648/4885CA12 4041/4885CA9 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.