Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.62 |
| ▸ | HTT | P42858 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | GLA | P06280 | 6/20 | 0.59 |
| ▸ | ATM | Q13315 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KLK7 | P49862 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 6/20 | 0.53 |
| ▸ | CASP7 | P55210 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634602 | 0.86 | CCR4 (0.50) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL20677688 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL37694 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL29351705 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL11296750 | 0.81 | ALDH1A1 (0.78) | ALDH1A1KDM4EHTTTDP1GLA | |
| Ethylene SCHEMBL28055534 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL24861952 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL12651890 | 0.78 | ALDH1A1 (0.72) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL24589860 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4EHTTTDP1GLA | |
| SCHEMBL700677 | 0.77 | ALDH1A1 (0.73) | ALDH1A1KDM4EHTTTDP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270651-B1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INST OF TECHN (US) | 1994-06-15 | — | — | EP | claimed |
| US-5118802-A | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | claimed |
| EP-0270651-A4 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1989-03-29 | — | — | EP | claimed |
| EP-0270651-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1988-06-15 | — | — | EP | claimed |
| WO-1988000201-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) | 1988-01-14 | — | — | WO | claimed |
| CN-111433606-B | Determination with different pitch heights | 上海宜晟生物科技有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-112218720-A | Homogeneous assay | ESSENLIX公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112218939-A | Rapid change in sample temperature for assay | ESSENLIX公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-111433606-A | Using determination of different pitch heights | ESSENLIX公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-110998325-A | Amplification assay | ESSENLIX公司 | 2020-04-10 | — | — | CN | disclosed |
| EP-0270651-B1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INST OF TECHN (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5118800-A | Oligonucleotides possessing a primary amino group in the terminal nucleotide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5118802-A | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5015733-A | Phosphoramidites and oligonucleotides derived therefrom | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4849513-A | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0270651-A4 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0270651-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988000201-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) | 1988-01-14 | — | — | WO | disclosed |