Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397136 | 0.87 | PIK3CD (0.37) | PIK3CDTAAR1PIK3CBPIK3CA | |
| SCHEMBL17397079 | 0.86 | PIK3CD (0.42) | PIK3CDTAAR1PIK3CBPIK3CA | |
| SCHEMBL17397072 | 0.79 | TAAR1 (0.40) | PIK3CDTAAR1KDM4E | |
| SCHEMBL17397110 | 0.77 | PIK3CD (0.43) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL17397228 | 0.75 | PIK3CD (0.55) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL17397176 | 0.73 | PIK3CD (0.41) | PIK3CDTAAR1PIK3CBPIK3CA | |
| SCHEMBL17397164 | 0.73 | PIK3CD (0.43) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL17397294 | 0.71 | PIK3CD (0.46) | PIK3CDTAAR1PIK3CBPIK3CA | |
| SCHEMBL17397082 | 0.71 | PIK3CD (0.42) | PIK3CDPIK3CBPIK3CAKDM4E | |
| SCHEMBL17397141 | 0.69 | PIK3CD (0.52) | PIK3CDPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164400-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | Lupin Limited (IN) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001855-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2016-01-07 | — | — | WO | disclosed |