Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397176 | 0.92 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBTAAR1 | |
| SCHEMBL17397202 | 0.85 | PIK3CA (0.40) | PIK3CDPIK3CAPIK3CBTAAR1 | |
| SCHEMBL17397271 | 0.83 | TAAR1 (0.42) | PIK3CDPIK3CAPIK3CBTAAR1 | |
| SCHEMBL17397174 | 0.83 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBTAAR1 | |
| SCHEMBL18989093 | 0.80 | HTR2A (0.33) | PIK3CDPIK3CAPIK3CBTAAR1 | |
| SCHEMBL17397293 | 0.78 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17397122 | 0.77 | TAAR1 (0.37) | PIK3CDPIK3CAPIK3CBTAAR1 | |
| SCHEMBL17397253 | 0.76 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17397160 | 0.75 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17397287 | 0.74 | PIM1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164400-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | Lupin Limited (IN) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001855-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2016-01-07 | — | — | WO | disclosed |