Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397885 | 0.88 | KDM4E (0.33) | ALDH1A1HSD17B10HPGDERN1 | |
| SCHEMBL20861759 | 0.79 | GSK3B (0.33) | GSK3BALDH1A1TDP1HSD17B10MAPT | |
| SCHEMBL15077376 | 0.77 | MEN1 (0.39) | ALDH1A1TDP1LMNAERN1KMT2A | |
| SCHEMBL20861758 | 0.77 | ERN1 (0.35) | ERN1 | |
| SCHEMBL983266 | 0.73 | AOC3 (0.50) | ALDH1A1HSD17B10LMNAHPGDMAPT | |
| SCHEMBL17397902 | 0.73 | LMNA (0.47) | ALDH1A1TDP1HSD17B10LMNAHPGD | |
| SCHEMBL12665647 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNAERN1KMT2A | |
| SCHEMBL29458861 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNAERN1KMT2A | |
| SCHEMBL983074 | 0.71 | AOC3 (0.40) | ALDH1A1LMNAHPGDMAPTAOC3 | |
| SCHEMBL24456050 | 0.71 | NQO2 (0.34) | GSK3BNQO2TXNRD1TXNRD3TXNRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164404-B1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO CO LTD (JP) | 2019-04-03 | — | — | EP | disclosed |
| US-9944660-B2 | Tricyclic benzoxaboroles as antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-04-17 | — | — | US | disclosed |
| US-9944660-B2 | Tricyclic benzoxaboroles as antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-04-17 | — | — | US | disclosed |
| US-9944660-B2 | Tricyclic benzoxaboroles as antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-04-17 | — | — | US | disclosed |
| US-20170174709-A1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20170174709-A1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20170174709-A1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-06-22 | — | — | US | disclosed |
| EP-3164404-A1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001834-A1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-01-07 | — | — | WO | disclosed |
| WO-2016001834-A1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174709-A1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | REN, ALPI, IKBKE | GSK3B 523/4885ALDH1A1 2153/4885TDP1 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.