Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 16/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399096 | 0.89 | SLC6A9 (0.52) | SLC6A9NPY5RTRPV1 | |
| SCHEMBL16473210 | 0.89 | SLC6A9 (0.52) | SLC6A9NPY5RTRPV1 | |
| SCHEMBL16659175 | 0.89 | SLC6A9 (0.52) | SLC6A9NPY5RTRPV1 | |
| SCHEMBL17399092 | 0.88 | TRPV1 (0.46) | SLC6A9TRPV1 | |
| SCHEMBL15544210 | 0.87 | MTNR1A (0.48) | NPY5RTRPV1 | |
| SCHEMBL17399094 | 0.77 | TRPV1 (0.43) | SLC6A9NPY5RTRPV1 | |
| SCHEMBL15545336 | 0.76 | TRPV1 (0.49) | SLC6A9NPY5RTRPV1 | |
| SCHEMBL15324092 | 0.76 | SLC6A9 (0.41) | SLC6A9NPY5RTRPV1 | |
| SCHEMBL15323975 | 0.76 | SLC6A9 (0.43) | SLC6A9NPY5RTRPV1 | |
| Hydrochloric Acid SCHEMBL3100983 | 0.76 | SLC6A9 (0.40) | SLC6A9NPY5RTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145197-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. | 2016-05-26 | — | — | US | disclosed |
| US-9227901-B2 | Process for preparing bicyclic amine derivatives | ABBVIE INC. (US) | 2016-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145197-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | HRH4, HRH3, HRH1 | SLC6A9 2885/4885NPY5R 1189/4885TRPV1 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.