Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399289 | 0.88 | CHRM2 (0.31) | ALDH1A1KCNH2 | |
| SCHEMBL18065445 | 0.86 | PAOX (0.33) | ALDH1A1KCNH2 | |
| SCHEMBL17705678 | 0.86 | — | — | |
| SCHEMBL17705672 | 0.86 | ALOX15 (0.32) | ALDH1A1ALOX15 | |
| SCHEMBL15782719 | 0.81 | KCNH2 (0.35) | KDM5AKDM4CALDH1A1KCNH2 | |
| SCHEMBL17705691 | 0.81 | DNM1 (0.32) | KDM5AKDM4C | |
| SCHEMBL15782713 | 0.80 | — | — | |
| SCHEMBL17705674 | 0.79 | — | — | |
| SCHEMBL17705693 | 0.79 | — | — | |
| SCHEMBL15782709 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227917-B2 | Amine-containing lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-05 | — | — | US | disclosed |