Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399284 | 0.86 | KDM5A (0.35) | ALOX15ALDH1A1 | |
| SCHEMBL17705693 | 0.84 | — | — | |
| SCHEMBL17705674 | 0.84 | — | — | |
| SCHEMBL15782713 | 0.81 | — | — | |
| SCHEMBL15782715 | 0.78 | — | — | |
| SCHEMBL17705691 | 0.78 | DNM1 (0.32) | — | |
| SCHEMBL17399277 | 0.77 | CYP2C9 (0.40) | ALOX15KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL27427924 | 0.76 | EPHX1 (0.39) | ALOX15KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL18065288 | 0.75 | DNM1 (0.42) | ALOX15MEN1ALDH1A1KMT2A | |
| SCHEMBL17399289 | 0.74 | CHRM2 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | ALOX15 289/4885KDM4E 757/4885MEN1 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.