Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CD69 | Q07108 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PYGB | P11216 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337162 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL12295742 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL13498558 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL15616403 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL13541586 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL14823585 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL14450135 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL13773326 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL20626631 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL12733141 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773127-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| EP-2539451-B1 | COMPOSITIONS FOR TARGETED DELIVERY OF SIRNA | ARROWHEAD RES CORP (US) | 2016-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773127-B2 | Compounds and methods for treating bacterial infections | MMP8, ELANE, MPO | ALDH1A1 847/4885THRB 4653/4885MAPK1 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.