Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543275 | 0.86 | AHR (0.52) | CYP2D6HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL14574432 | 0.83 | CYP2D6 (0.51) | CYP2D6HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20274465 | 0.81 | HTT (0.60) | CYP2D6HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL8533400 | 0.80 | KIF11 (0.47) | HPGDCYP1A2CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL13096663 | 0.80 | CYP2D6 (0.53) | CYP2D6HPGDCYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL3097740 | 0.79 | CYP2D6 (0.52) | CYP2D6HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL17400293 | 0.77 | CYP2D6 (0.51) | CYP2D6HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL3096262 | 0.77 | CAPN1 (0.48) | CYP2D6HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL13097494 | 0.77 | CYP2D6 (0.46) | CYP2D6HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL13097490 | 0.76 | SIGMAR1 (0.49) | CYP2D6CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080757-A | TREATMENT OF HELICOBACTER (CAMPYLOBACTER) PYLORI INFECTIONS; TREATMENT AND PREVENTION OF PEPTIC ULCERS, GASTRITIS, DYSPEPSIA, AND GASTRIC CANCER | PFIZER INC (US) | 2000-06-27 | — | — | US | disclosed |
| EP-0811613-A1 | Antibiotic Quinolones and derivatives | PFIZER INC. (US) | 1997-12-10 | — | — | EP | disclosed |