Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.84 |
| ▸ | DGKA | P23743 | 1/20 | 0.65 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17401281 | 1.00 | DNM1 (0.84) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL17401285 | 1.00 | DNM1 (0.84) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL17401282 | 1.00 | DNM1 (0.84) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL17401283 | 1.00 | DNM1 (0.84) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL14239731 | 0.93 | DNM1 (0.83) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL17401275 | 0.93 | DNM1 (0.83) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL17401279 | 0.93 | DNM1 (0.83) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL17401277 | 0.93 | DNM1 (0.83) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL17401274 | 0.93 | DNM1 (0.83) | DNM1DGKAPAMNAAAPRSS1 | |
| SCHEMBL26970342 | 0.93 | DNM1 (0.83) | DNM1DGKAPAMNAAAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| WO-2016004202-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | WO | disclosed |
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | SGMS2, SGMS1, ARG2 | DNM1 2046/4885DGKA 117/4885PAM 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.