Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 4/20 | 0.53 |
| ▸ | THRA | P10827 | 2/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12120108 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL17401287 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL12120105 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL12120109 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL12120107 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL23864897 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL12120095 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL17401288 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL16541625 | 1.00 | DGKA (0.61) | DGKAALDH1A1L3MBTL1THRBTHRA | |
| SCHEMBL12120094 | 0.98 | DGKA (0.58) | DGKAALDH1A1L3MBTL1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| WO-2016004202-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | WO | disclosed |
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | SGMS2, SGMS1, ARG2 | DGKA 117/4885ALDH1A1 2532/4885L3MBTL1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.