Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17403869 | 1.00 | KDM4E (0.62) | KDM4ELMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL6809240 | 0.88 | CA2 (0.49) | KDM4ELMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL6809242 | 0.88 | CA2 (0.49) | KDM4ELMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL18285162 | 0.88 | CA2 (0.49) | KDM4ELMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL27536297 | 0.88 | CA2 (0.49) | KDM4ELMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL17403870 | 0.84 | KDM4E (0.55) | KDM4ELMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL17404087 | 0.84 | KDM4E (0.55) | KDM4ELMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL9829969 | 0.82 | PYGL (0.54) | KDM4ELMNAALDH1A1CA2CA1 | |
| SCHEMBL9829960 | 0.82 | PYGL (0.54) | KDM4ELMNAALDH1A1CA2CA1 | |
| SCHEMBL29885579 | 0.82 | MMP2 (0.50) | KDM4ELMNAHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002269-A1 | LANTHANIDE CLUSTERS AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002269-A1 | LANTHANIDE CLUSTERS AND METHODS OF USE THEREOF | VAC14, LPXN, SLC39A7 | KDM4E 2416/4885LMNA 242/4885HPGD 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.