Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622791 | 1.00 | LTA4H (0.42) | LTA4HCPB1ALDH1A1MEN1KMT2A | |
| SCHEMBL622437 | 0.87 | CPB1 (0.40) | CPB1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL622780 | 0.82 | FGFR1 (0.42) | LTA4HALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL16566545 | 0.78 | TSHR (0.55) | ALDH1A1MEN1KMT2ANPSR1TAAR1 | |
| SCHEMBL3792033 | 0.77 | KMT2A (0.41) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL620001 | 0.77 | KMT2A (0.41) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL708006 | 0.73 | CPB1 (0.56) | LTA4HCPB1ALDH1A1KDM4E | |
| SCHEMBL15662772 | 0.73 | LTA4H (0.51) | LTA4HALDH1A1KMT2ANPSR1KDM4E | |
| SCHEMBL709053 | 0.72 | CPB1 (0.62) | LTA4HCPB1ALDH1A1 | |
| SCHEMBL706633 | 0.72 | CPB1 (0.62) | LTA4HCPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389376-A1 | NOVEL BICYCLIC ANTIBIOTICS | Basilea Pharmaceutica AG (CH) | 2011-11-30 | — | — | EP | disclosed |
| WO-2010084152-A1 | NOVEL BICYCLIC ANTIBIOTICS | BASILEA PHARMACEUTICA AG (CH) | 2010-07-29 | — | — | WO | disclosed |