SCHEMBL17407653

SCHEMBL17407653

CC(CO)Oc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.42
ADORA2A P29274 3/20 0.42
ADORA1 P30542 3/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ADORA2B P29275 1/20 0.42
EGFR P00533 1/20 0.41
GAA P10253 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40
CYP2C19 P33261 1/20 0.40
LMNA P02545 1/20 0.40
MAPK10 P53779 1/20 0.40
MAPT P10636 3/20 0.40
PRKAB2 O43741 1/20 0.39
PRKAG1 P54619 1/20 0.39
PRKAA2 P54646 1/20 0.39
PRKAA1 Q13131 1/20 0.39
PRKAG3 Q9UGI9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL807730 0.88 MAPT (0.41) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL31499114 0.87 RXRA (0.49) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL23610186 0.85 ALOX15 (0.42) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL9635566 0.84 MAPT (0.48) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL13474410 0.84 CYP1A2 (0.62) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL31260210 0.84 CYP1A2 (0.62) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL17357498 0.83 MAPT (0.47) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL13270945 0.83 GPR88 (0.43) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL5859402 0.83 TSHR (0.47) ADORA3ADORA2AADORA1ALOX15TSHR
SCHEMBL10034100 0.82 GAA (0.50) ADORA3ADORA2AADORA1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110352223-B Coating composition with covalently bound UV absorber 巴斯夫欧洲公司 2022-08-02 CN disclosed
US-20220135835-A1 COATING COMPOSITIONS HAVING COVALENTLY BOUND ULTRAVIOLET ABSORBERS BASF SE (DE) 2022-05-05 US disclosed
US-20220135835-A1 COATING COMPOSITIONS HAVING COVALENTLY BOUND ULTRAVIOLET ABSORBERS BASF SE (DE) 2022-05-05 US disclosed
US-11254837-B2 Coating compositions having covalently bound ultraviolet absorbers BASF SE 2022-02-22 US disclosed
US-11254837-B2 Coating compositions having covalently bound ultraviolet absorbers BASF SE 2022-02-22 US disclosed
US-20210206996-A1 COATING COMPOSITIONS HAVING COVALENTLY BOUND ULTRAVIOLET ABSORBERS BASF SE (DE) 2021-07-08 US disclosed
US-20210206996-A1 COATING COMPOSITIONS HAVING COVALENTLY BOUND ULTRAVIOLET ABSORBERS BASF SE (DE) 2021-07-08 US disclosed
EP-3615622-A1 COATING COMPOSITIONS HAVING COVALENTLY BOUND ULTRAVIOLET ABSORBERS BASF SE (DE) 2020-03-04 EP disclosed
WO-2018199927-A1 COATING COMPOSITIONS HAVING COVALENTLY BOUND ULTRAVIOLET ABSORBERS BASF SE (DE) 2018-11-01 WO disclosed
US-9593088-B2 Method for producing a polymerizable UV absorber COVESTRO DEUTSCHLAND AG (DE) 2017-03-14 US disclosed
US-9593088-B2 Method for producing a polymerizable UV absorber COVESTRO DEUTSCHLAND AG (DE) 2017-03-14 US disclosed
US-20160002181-A1 METHOD FOR PRODUCING A POLYMERIZABLE UV ABSORBER COVESTRO DEUTSCHLAND AG (DE) 2016-01-07 US disclosed
US-20160002181-A1 METHOD FOR PRODUCING A POLYMERIZABLE UV ABSORBER COVESTRO DEUTSCHLAND AG (DE) 2016-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002181-A1 METHOD FOR PRODUCING A POLYMERIZABLE UV ABSORBER MGMT, MMAB, UNG ADORA3 2115/4885ADORA2A 1677/4885ADORA1 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.