SCHEMBL17409183

SCHEMBL17409183

CCC(C)(C)c1ccc(S(=O)(=O)NS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.41
ALDH1A1 P00352 3/20 0.41
DRD2 P14416 1/20 0.40
DRD3 P35462 1/20 0.40
KCNH2 Q12809 1/20 0.40
CA2 P00918 6/20 0.40
CA1 P00915 5/20 0.40
CA12 O43570 3/20 0.39
CA9 Q16790 3/20 0.39
RORA P35398 1/20 0.38
NR3C2 P08235 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24088699 0.83 ALDH1A1 (0.59) PTPN11ALDH1A1CA2CA1RORA
SCHEMBL17953242 0.82 ALDH1A1 (0.44) ALDH1A1DRD2DRD3KCNH2CA2
SCHEMBL18387060 0.81 CA2 (0.50) PTPN11ALDH1A1CA2CA1CA12
SCHEMBL13588301 0.80 CA1 (0.50) CA2CA1CA12CA9SMN1; SMN2
SCHEMBL10180000 0.78 ALDH1A1 (0.46) PTPN11ALDH1A1DRD2DRD3KCNH2
SCHEMBL7697391 0.76 CA2 (0.52) CA2CA1MMP1
SCHEMBL12386314 0.76 GAA (0.53) ALDH1A1CA2CA1CA12CA9
SCHEMBL18382680 0.76 CA2 (0.44) PTPN11ALDH1A1CA2CA1CA12
SCHEMBL17409185 0.76 CA2 (0.58) PTPN11CA2CA1SMN1; SMN2NPC1
SCHEMBL19018116 0.76 DRD2 (0.31) ALDH1A1DRD2DRD3KCNH2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9720319-B2 Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2017-08-01 US disclosed
US-9671687-B2 Coloring composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, and image display device FUJIFILM CORPORATION (JP) 2017-06-06 US disclosed
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION FUJIFILM CORPORATION (JP) 2016-12-29 US disclosed
US-20160327858-A1 COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-11-10 US disclosed
US-20160327859-A1 COLORING COMPOSITION, AND CURED FILM, COLOR FILTER, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, AND DYE MULTIMER, EACH USING THE COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2016-11-10 US disclosed
US-20160216604-A1 COLORED COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-07-28 US disclosed
US-20160004154-A1 RADIATION-SENSITIVE COLORED COMPOSITIONS, CURED COLORED FILMS, COLOR FILTERS, PROCESSES FOR FORMING COLORED PATTERNS, PROCESSES FOR PREPARING COLOR FILTERS, SOLID-STATE IMAGE SENSORS AND LIQUID CRYSTAL DISPLAY DEVICES FUJIFILM CORPORATION (JP) 2016-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION O60361, WDR12, SEM1 PTPN11 2098/4885ALDH1A1 2079/4885DRD2 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.