Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 14/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409456 | 0.83 | KDR (0.57) | KDRPDGFRB | |
| SCHEMBL17409489 | 0.76 | KDR (0.60) | KDRPDGFRBAPP | |
| SCHEMBL17409486 | 0.74 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17424244 | 0.74 | KDR (0.55) | KDRPDGFRBDYRK1A | |
| SCHEMBL17409482 | 0.73 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL22121658 | 0.72 | DYRK1A (0.47) | KDRPDGFRBDYRK1A | |
| SCHEMBL1051267 | 0.69 | DYRK1A (0.52) | KDRPDGFRBDYRK1A | |
| SCHEMBL2518335 | 0.68 | KDR (0.57) | KDRPDGFRBDYRK1A | |
| SCHEMBL9611200 | 0.65 | APP (1.00) | APP | |
| SCHEMBL864945 | 0.65 | APP (1.00) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |