Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | IL18 | Q14116 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424508 | 0.92 | CYP2C9 (0.67) | CYP2C9MAPTTSHRRAB9AMEN1 | |
| SCHEMBL1542345 | 0.88 | ALDH1A1 (0.58) | CYP2C9MAPTLMNATSHRHTT | |
| SCHEMBL8319331 | 0.84 | CYP2C9 (0.50) | CYP2C9MAPTLMNATSHRHTT | |
| SCHEMBL13132664 | 0.84 | CYP2C9 (0.48) | CYP2C9LMNARAB9AMEN1KMT2A | |
| SCHEMBL13132517 | 0.84 | CYP2C9 (0.48) | CYP2C9LMNARAB9AMEN1KMT2A | |
| SCHEMBL17316271 | 0.84 | CYP2C9 (0.58) | CYP2C9MAPTMEN1KMT2ACA12 | |
| SCHEMBL12846187 | 0.83 | CA12 (0.55) | CYP2C9LMNARAB9AMEN1KMT2A | |
| SCHEMBL13168736 | 0.83 | CYP2C9 (0.43) | CYP2C9MAPTLMNATSHRHTT | |
| SCHEMBL474661 | 0.83 | KMT2A (0.70) | MAPTLMNATSHRHTTRAB9A | |
| SCHEMBL4552493 | 0.83 | PEPD (0.57) | CYP2C9MAPTLMNARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |