Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213080 | 0.89 | NPC1 (0.44) | NPC1RAB9AKMT2ARXFP1POLB | |
| SCHEMBL16293630 | 0.84 | NPC1 (0.41) | NPC1RAB9AKMT2ARXFP1POLB | |
| SCHEMBL17409842 | 0.84 | NPC1 (0.41) | NPC1RAB9AKMT2ARXFP1POLB | |
| SCHEMBL18932460 | 0.84 | NPC1 (0.51) | NPC1RAB9AKMT2ARXFP1POLB | |
| SCHEMBL17409846 | 0.78 | NPC1 (0.46) | NPC1RAB9AKMT2ARXFP1POLB | |
| SCHEMBL16915424 | 0.76 | NPC1 (0.42) | NPC1RAB9AKMT2ARXFP1POLB | |
| SCHEMBL16212492 | 0.75 | SMN1; SMN2 (0.33) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL10504321 | 0.74 | SMN1; SMN2 (0.58) | NPC1RAB9AKMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL1458165 | 0.72 | NPC1 (0.44) | NPC1RAB9AKMT2ARXFP1POLB | |
| SCHEMBL29182511 | 0.71 | KMT2A (0.41) | NPC1RAB9AKMT2ARXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160946-B1 | HERBICIDAL BENZOIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | disclosed |
| US-9988359-B2 | Herbicidally active benzoic acid amides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-05 | — | — | US | disclosed |
| US-20170197926-A1 | HERBICIDALLY ACTIVE BENXZOIC ACID AMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-13 | — | — | US | disclosed |
| WO-2016001074-A1 | HERBICIDALLY ACTIVE BENZOIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2016-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197926-A1 | HERBICIDALLY ACTIVE BENXZOIC ACID AMIDES | AOX1, GABRA5, GABRD | NPC1 4588/4885RAB9A 3263/4885KMT2A 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.