Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | GRK1 | Q15835 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17413884 | 0.84 | TSHR (0.71) | TSHRALDH1A1HSD17B10USP2GRK2 | |
| SCHEMBL17413874 | 0.82 | TSHR (0.59) | TSHRALDH1A1HSD17B10USP2GUSB | |
| SCHEMBL17413871 | 0.81 | TSHR (1.00) | TSHRALDH1A1PKMUSP2 | |
| SCHEMBL2572783 | 0.80 | TSHR (0.66) | TSHRALDH1A1HSD17B10USP2GUSB | |
| SCHEMBL17413861 | 0.80 | TSHR (0.67) | TSHRALDH1A1USP2GUSB | |
| SCHEMBL7690354 | 0.76 | ALDH1A1 (0.66) | ALDH1A1PKMHSD17B10GUSB | |
| SCHEMBL19752621 | 0.75 | TSHR (0.76) | TSHRALDH1A1PKMHSD17B10GUSB | |
| SCHEMBL19752620 | 0.75 | TSHR (0.76) | TSHRALDH1A1PKMHSD17B10GUSB | |
| SCHEMBL16366977 | 0.75 | HTT (0.69) | TSHRALDH1A1PKMHSD17B10HTT | |
| SCHEMBL11979758 | 0.72 | MAPK14 (0.76) | MAOAROCK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004028-A1 | 2-OXOPYRIMIDINE-5-CARBOXYLATE DERIVATIVES FOR TREATING THYROID DISEASES | LATIF RAUF (US) | 2016-01-07 | — | — | WO | disclosed |