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SCHEMBL17414967

SCHEMBL17414967

CC(C)(C)c1cccc(-c2cccc3c2C=CC3[Hf](C)(C)(=[SiH2])(C2C=Cc3c(-c4cccc(C(C)(C)C)c4)cccc32)(C(C)(C)C)C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 1/20 0.35
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ HTR1A P08908 1/20 0.31
▸ HTR7 P34969 1/20 0.31
▸ PTAFR P25105 1/20 0.30
▸ PTPN5 P54829 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415049 0.93 RXRA (0.33) KIF11RXRARXRB
SCHEMBL17415931 0.91 KIF11 (0.36) KIF11RXRARXRBPTAFRPTPN5
SCHEMBL17415221 0.89 BRD4 (0.32) KIF11
SCHEMBL17415818 0.87 RXRA (0.33) KIF11RXRARXRB
SCHEMBL17415141 0.87 KIF11 (0.33) KIF11RXRARXRB
SCHEMBL17415385 0.87 KIF11 (0.33) KIF11RXRARXRB
SCHEMBL17415181 0.86 CA12 (0.33) —
SCHEMBL17415558 0.86 RXRA (0.33) KIF11RXRARXRBPTAFRPTPN5
SCHEMBL17415618 0.86 RXRA (0.33) KIF11RXRARXRBPTAFRPTPN5
SCHEMBL17416060 0.85 HTR1A (0.31) HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 — — EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 — — EP disclosed