SCHEMBL17415359

SCHEMBL17415359

Cc1cccc(-c2cccc3c2C=CC3[Hf](C)(C)(C2C=Cc3c(-c4cccc(C)c4)cccc32)=[Si](c2ccccc2)c2ccccc2)c1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.32
ENPP3 O14638 1/20 0.32
ADORA2A P29274 1/20 0.32
CNR2 P34972 2/20 0.32
CNR1 P21554 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
KMT2A Q03164 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415791 0.92
SCHEMBL17416100 0.90 CHRNB2 (0.32)
SCHEMBL17415715 0.89 ADORA1 (0.34) ADORA1ENPP3ADORA2ACNR2CNR1
SCHEMBL17414991 0.88 EDNRB (0.32)
SCHEMBL17415617 0.85 RXRA (0.32)
SCHEMBL17415443 0.85 BRD4 (0.34)
SCHEMBL17415550 0.85 CHEK1 (0.32)
SCHEMBL17415283 0.85 ALDH1A1 (0.31) NPC1KMT2AHPGD
SCHEMBL17415090 0.83 MAOB (0.32)
SCHEMBL17415943 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed