SCHEMBL17415548

SCHEMBL17415548

Cc1cccc(-c2cccc3c2C=C2C3[Hf](C)(C)C3C(=Cc4c(-c5cccc(C)c5)cccc43)[Si]2(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.32
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
CHEK1 O14757 1/20 0.32
MAP4K4 O95819 1/20 0.32
ABL1 P00519 1/20 0.32
NTRK1 P04629 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
CSF1R P07333 1/20 0.32
MET P08581 1/20 0.32
PDGFRB P09619 1/20 0.32
PIM1 P11309 1/20 0.32
FGFR1 P11362 1/20 0.32
PDGFRA P16234 1/20 0.32
PRKACA P17612 1/20 0.32
LTK P29376 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415854 0.91
SCHEMBL17415088 0.88
SCHEMBL18760124 0.88
SCHEMBL17414952 0.87 MAOB (0.31) MAOBNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17414885 0.87 ADRA2A (0.32) MAOBNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17415713 0.87 ADORA1 (0.33) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL17416007 0.86 ADORA3 (0.31)
SCHEMBL17414970 0.86 CHRNB2 (0.31)
SCHEMBL17415175 0.86 CNR1 (0.32) MAOB
SCHEMBL17415208 0.86 BRD4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed