SCHEMBL17415928

SCHEMBL17415928

C[Si](C)=[Hf](C)(C)(C1C=Cc2c(-c3cccc(C(C)(C)C)c3)cccc21)C1C=Cc2c(-c3cccc(C(C)(C)C)c3)cccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.35
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415162 0.91 RXRA (0.30) RXRARXRB
SCHEMBL17414963 0.89 KIF11 (0.34) KIF11RXRARXRB
SCHEMBL17415138 0.89 KIF11 (0.32) KIF11
SCHEMBL17415541 0.88 BRD4 (0.34)
SCHEMBL17415556 0.88 RXRA (0.32) KIF11RXRARXRB
SCHEMBL17415383 0.87 KIF11 (0.33) KIF11RXRARXRB
SCHEMBL17415817 0.87 KIF11 (0.33) KIF11RXRARXRB
SCHEMBL17414919 0.87 CTSS (0.32) KIF11RXRARXRB
SCHEMBL17415617 0.86 RXRA (0.32) KIF11RXRARXRB
SCHEMBL17415395 0.85 CTSS (0.31) RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed