Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416214 | 1.00 | DNM1 (0.54) | DNM1ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL17416110 | 0.92 | DNM1 (0.48) | DNM1ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL17416208 | 0.92 | DNM1 (0.48) | DNM1ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL17416199 | 0.86 | CES2 (0.39) | DNM1TSHRTHRBCES2HSD17B10 | |
| SCHEMBL17416198 | 0.86 | CES2 (0.39) | DNM1TSHRTHRBCES2HSD17B10 | |
| SCHEMBL23132630 | 0.83 | DNM1 (0.64) | DNM1ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL20137213 | 0.83 | DNM1 (0.56) | DNM1ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL17817257 | 0.83 | DNM1 (0.56) | DNM1ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL6827760 | 0.83 | DNM1 (0.56) | DNM1ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL11209342 | 0.83 | DNM1 (0.79) | DNM1ALDH1A1TSHRTHRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204076-A1 | SYNTHESIS AND USE OF AMINO LIPIDS | SCREENFECT GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| US-20170204076-A1 | SYNTHESIS AND USE OF AMINO LIPIDS | SCREENFECT GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| US-20170204076-A1 | SYNTHESIS AND USE OF AMINO LIPIDS | SCREENFECT GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| EP-2966068-A1 | Synthesis and use of amino lipids | Incella GmbH (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2966068-A1 | Synthesis and use of amino lipids | Incella GmbH (DE) | 2016-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204076-A1 | SYNTHESIS AND USE OF AMINO LIPIDS | ACSL4, PYM1, LPAR4 | DNM1 1719/4885ALDH1A1 4417/4885TSHR 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.