Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17025773 | 0.82 | POLB (0.43) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL17416645 | 0.82 | KMT2A (0.37) | KDM4EMEN1KMT2ALMNACD274 | |
| SCHEMBL5058529 | 0.82 | ABCB1 (0.48) | MAPK1L3MBTL1KDM4EMEN1AHR | |
| SCHEMBL17416629 | 0.81 | CTSD (0.43) | KDM4ELMNA | |
| SCHEMBL9100311 | 0.81 | RAB9A (0.43) | LMNASMN1; SMN2 | |
| SCHEMBL2482845 | 0.78 | ABCB1 (0.51) | — | |
| SCHEMBL18091865 | 0.77 | NPC1 (0.48) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL17416613 | 0.76 | MAPK1 (0.42) | MAPK1L3MBTL1KDM4EMEN1AHR | |
| SCHEMBL18091874 | 0.76 | MAPT (0.43) | KDM4EMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9102868 | 0.76 | TSHR (0.40) | KDM4EMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |