SCHEMBL17417873

SCHEMBL17417873

C=CCn1c2ccc(N)cc2c2cc(N)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
HBB P68871 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
EGFR P00533 1/20 0.40
POLB P06746 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
HCRTR1 O43613 2/20 0.36
NPC1 O15118 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2355430 0.92 ALDH1A1 (0.64) MAPTKDM4EALDH1A1HPGDMEN1
Benzene SCHEMBL28118473 0.83 MEN1 (0.54) MAPTKDM4EALDH1A1HPGDMEN1
SCHEMBL8158727 0.77 MAPT (0.40) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL3370631 0.77 MAPT (0.50) MAPTKDM4EALDH1A1HPGDKMT2A
SCHEMBL11825251 0.77 MAPT (0.47) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL8221481 0.74 PTGER4 (0.54) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL30849652 0.74 PTGER4 (0.54) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL30849653 0.74 MAPT (0.44) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL4228486 0.74 MAPT (0.44) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL7979590 0.74 KDM4E (0.59) MAPTKDM4EALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10545387-B2 Electrochromic device for applying voltage to electrodes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-01-28 US claimed
US-20160011482-A1 ELECTROCHROMIC DEVICE COMPRISING THREE OR FOUR LAYERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-01-14 US claimed
US-10545387-B2 Electrochromic device for applying voltage to electrodes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-01-28 US disclosed
US-20160011482-A1 ELECTROCHROMIC DEVICE COMPRISING THREE OR FOUR LAYERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-01-14 US disclosed