Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221481 | 1.00 | PTGER4 (0.54) | PTGER4MAPTCYP2A6POLBMEN1 | |
| SCHEMBL7132029 | 0.92 | PTGER4 (0.60) | PTGER4MAPTPOLBMEN1KMT2A | |
| SCHEMBL8158727 | 0.85 | MAPT (0.40) | PTGER4MAPTPOLBMEN1KMT2A | |
| SCHEMBL29002800 | 0.82 | PTGER4 (0.50) | PTGER4MAPTPOLBMEN1KMT2A | |
| SCHEMBL604579 | 0.78 | HTT (0.48) | PTGER4MAPTPOLBMEN1KMT2A | |
| SCHEMBL29794143 | 0.78 | PTGER4 (0.81) | PTGER4MAPTCYP2A6POLBMEN1 | |
| SCHEMBL4832600 | 0.78 | PTGER4 (0.81) | PTGER4MAPTCYP2A6POLBMEN1 | |
| SCHEMBL15823510 | 0.74 | ADORA3 (0.37) | PTGER4MAPTCYP2A6POLBMEN1 | |
| SCHEMBL15822463 | 0.74 | MIF (0.42) | POLBCYP3A4NPC1LMNA | |
| SCHEMBL17417873 | 0.74 | MAPT (0.50) | PTGER4MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624062-A | Barbiturates structure-containing compound and preparation method and application thereof | 武汉大学 | 2024-03-01 | — | — | CN | disclosed |