Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | RORB | Q92753 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849653 | 1.00 | MAPT (0.44) | MAPTPGRRORARORCRORB | |
| SCHEMBL26500398 | 0.84 | PGR (0.43) | MAPTPGRRORARORCRORB | |
| SCHEMBL26144555 | 0.77 | PGR (0.53) | MAPTPGRRORARORCRORB | |
| SCHEMBL30849654 | 0.77 | PGR (0.53) | MAPTPGRRORARORCRORB | |
| SCHEMBL27798318 | 0.76 | PGR (0.49) | MAPTPGRRORARORCRORB | |
| SCHEMBL4026771 | 0.76 | HTR1D (0.41) | MAPTPGRRORARORCRORB | |
| SCHEMBL15081186 | 0.74 | PTGES2 (0.46) | MAPTPGRRORARORCRORB | |
| SCHEMBL11825251 | 0.74 | MAPT (0.47) | MAPTALDH1A1GAAATML3MBTL1 | |
| SCHEMBL17417873 | 0.74 | MAPT (0.50) | MAPTALDH1A1GAAHPGDATM | |
| SCHEMBL8158727 | 0.74 | MAPT (0.40) | MAPTALDH1A1PKMATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609258-B2 | Light emitting devices and compositions | NITTO DENKO CORPORATION (JP) | 2013-12-17 | — | — | US | disclosed |
| US-20120305895-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2012-12-06 | — | — | US | disclosed |
| US-20120305895-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2012-12-06 | — | — | US | disclosed |
| US-20120305895-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2012-12-06 | — | — | US | disclosed |
| US-20090066234-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090066234-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| WO-2009006550-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-01-08 | — | — | WO | disclosed |
| WO-2009006550-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090066234-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | MAP1LC3A, MAP1LC3C, CRY1 | MAPT 53/4885PGR 2698/4885RORA 409/4885 |
| US-20120305895-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | ILK, CRY1, IK | MAPT 251/4885PGR 2213/4885RORA 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.