Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30189537 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4ECA2TDP1 | |
| SCHEMBL16132341 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL21596184 | 0.84 | TRPV1 (0.36) | ALDH1A1KMT2AKDM4ECA2TDP1 | |
| SCHEMBL30189502 | 0.84 | PLAU (0.40) | ALDH1A1KMT2AKDM4ECA2TDP1 | |
| SCHEMBL364453 | 0.83 | KDM4E (0.48) | ALDH1A1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL29583655 | 0.83 | KDM4E (0.48) | ALDH1A1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL25428853 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4ECA2TDP1 | |
| SCHEMBL16132299 | 0.80 | CYP2A6 (0.61) | ALDH1A1KDM4ECYP2A6LMNAHTT | |
| SCHEMBL16132361 | 0.80 | KDM4E (0.46) | ALDH1A1KMT2AKDM4ETRPV1 | |
| SCHEMBL30578381 | 0.79 | PTPRC (0.46) | ALDH1A1KMT2AKDM4ECA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947646-B | Method for hydroxylation of aryl or heteroaryl halides by photocatalysis | 浙江工业大学 | 2024-07-23 | — | — | CN | claimed |
| CN-118325184-A | Environment-friendly high-flame-retardance sponge and preparation method thereof | 伟建实业(苏州)有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118063466-A | 5-Cyano pyrazolo [1,5-a ] pyrimidine compound and synthetic method thereof | 皖西学院 | 2024-05-24 | — | — | CN | claimed |
| CN-111433211-B | Synthesis of halichondrin | 哈佛大学的校长及成员们 | 2024-05-07 | — | — | CN | claimed |
| CN-117964579-A | Method for preparing epoxypropane and co-producing carboxylic acid by propylene epoxidation | 中山大学 | 2024-05-03 | — | — | CN | claimed |
| CN-117756843-A | Preparation method of alkyl germanium based on olefin difunctional | 南京信息工程大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117645581-A | Method for synthesizing series of functional groups of photocatalytic inert C (sp 3) -H bond | 浙江工业大学台州研究院 | 2024-03-05 | — | — | CN | claimed |
| CN-117623925-A | Method for deoxidizing and converting photocatalytic alcohol | 同济大学 | 2024-03-01 | — | — | CN | claimed |
| US-11905287-B2 | 4-substitued cytisine analogues | THE UNIVERSITY OF BRISTOL (GB) | 2024-02-20 | — | — | US | claimed |
| CN-115572240-B | Mechanical force synthesis method for constructing C-C bond by three-component reduction cross coupling | 西安交通大学 | 2024-01-26 | — | — | CN | claimed |
| CN-111018708-A | Synthesis method of difluoroalkyl substituted aromatic ketone compound under photocatalysis | 浙江工业大学 | 2020-04-17 | — | — | CN | claimed |
| CN-110983368-A | Synthesis method of nickel-catalyzed C-3 alkyl substituted quinoxalinone under electrochemical condition | 北京工业大学 | 2020-04-10 | — | — | CN | claimed |
| CN-110845291-A | Method for catalytic reduction of alkyne into olefin by visible light induction | 江西科技师范大学 | 2020-02-28 | — | — | CN | claimed |
| CN-110803972-A | Synthesis method of difluoroalkyl substituted aromatic aldehyde compound under photocatalysis | 浙江工业大学 | 2020-02-18 | — | — | CN | claimed |
| US-10544098-B2 | Method for synthesizing bipyridine compound and method for manufacturing pyridine compound | KOBELCO ECO-SOLUTIONS CO., LTD. (JP) | 2020-01-28 | — | — | US | claimed |
| CN-110724033-A | Method for preparing alcohol by Suzuki reaction without exogenous base | 滁州学院 | 2020-01-24 | — | — | CN | claimed |
| CN-110088106-A | Compound | 布里斯托大学 | 2019-08-02 | — | — | CN | claimed |
| EP-3500572-A2 | CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION | The University Of Bristol (GB) | 2019-06-26 | — | — | EP | claimed |
| US-20180282278-A1 | METHOD FOR SYNTHESIZING BIPYRIDINE COMPOUND AND METHOD FOR MANUFACTURING PYRIDINE COMPOUND | KOBELCO ECO-SOLUTIONS CO., LTD. (JP) | 2018-10-04 | — | — | US | claimed |
| WO-2018033742-A2 | COMPOUNDS | THE UNIVERSITY OF BRISTOL (GB) | 2018-02-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544098-B2 | Method for synthesizing bipyridine compound and method for manufacturing pyridine compound | TBCD, QDPR, BRD2 | ALDH1A1 2295/4885KMT2A 1711/4885KDM4E 1353/4885 |
| US-11905287-B2 | 4-substitued cytisine analogues | CES2, CDA, PCYT1A | ALDH1A1 1941/4885KMT2A 976/4885KDM4E 1310/4885 |
| US-20180282278-A1 | METHOD FOR SYNTHESIZING BIPYRIDINE COMPOUND AND METHOD FOR MANUFACTURING PYRIDINE COMPOUND | TBCD, QDPR, BRD2 | ALDH1A1 2295/4885KMT2A 1711/4885KDM4E 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.