Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | PGR | P06401 | 3/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | SHBG | P04278 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604525 | 0.99 | LMNA (0.73) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL21067996 | 0.91 | MAPT (0.84) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL23752494 | 0.88 | MAPT (0.78) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL17419472 | 0.88 | MAPT (0.78) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL11854733 | 0.87 | LMNA (0.59) | LMNAMAPTCYP3A4PGRAR | |
| Cyclohexane SCHEMBL8027519 | 0.87 | MAPT (0.76) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL343128 | 0.86 | MAPT (0.79) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL17419490 | 0.86 | MAPT (0.98) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL11121455 | 0.85 | MAPT (0.75) | LMNAMAPTCYP3A4PGRAR | |
| SCHEMBL5155074 | 0.85 | LMNA (0.55) | LMNAMAPTCYP3A4PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250281509-A1 | SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER | THE JOHNS HOPKINS UNIVERSTY | 2025-09-11 | — | — | US | disclosed |
| US-20160008376-A1 | Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders | BIOCOPEA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| WO-2016005599-A1 | COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS | BIOCOPEA LIMITED (GB) | 2016-01-14 | — | — | WO | disclosed |