Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 8/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.36 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.36 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.36 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.36 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751069 | 0.79 | HTR2C (0.56) | TAAR1HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL6601826 | 0.75 | HTR2C (0.54) | TAAR1HTR2AHTR2CHTR2BTSHR | |
| Glucuronic Acid SCHEMBL161811 | 0.74 | TAAR1 (0.38) | TAAR1HTR2AHTR2CHTR2BTSHR | |
| Glucuronic Acid SCHEMBL164771 | 0.74 | TAAR1 (0.38) | TAAR1HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL2369359 | 0.71 | HTR2C (0.50) | TAAR1HTR2AHTR2CHTR2BTSHR | |
| Cadaverine Tartrate SCHEMBL1668270 | 0.69 | PRCP (0.73) | TSHRNPSR1DRD1DRD2PRCP | |
| Cadaverine Tartrate SCHEMBL1477981 | 0.69 | PRCP (0.73) | TSHRNPSR1DRD1DRD2PRCP | |
| SCHEMBL4662681 | 0.68 | HTR2C (0.50) | TAAR1HTR2AHTR2CHTR2BTSHR | |
| Cadaverine Tartrate SCHEMBL3717811 | 0.68 | PNMT (0.66) | HTR2CPRCP | |
| SCHEMBL7698264 | 0.67 | HTR2A (0.51) | TAAR1HTR2AHTR2CHTR2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611449-A1 | ADMINISTRATION OF LORCASERIN TO INDIVIDUALS WITH RENAL IMPAIRMENT | Arena Pharmaceuticals, Inc. (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030939-A1 | ADMINISTRATION OF LORCASERIN TO INDIVIDUALS WITH RENAL IMPAIRMENT | ARENA PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |