Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 6/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266848 | 0.83 | CAPN1 (0.58) | CTSBCAPN1ACE | |
| SCHEMBL5563236 | 0.83 | CAPN1 (0.58) | CTSBCAPN1ACE | |
| SCHEMBL2269431 | 0.83 | CAPN1 (0.58) | CTSBCAPN1ACE | |
| SCHEMBL14290145 | 0.83 | CAPN1 (0.56) | NPC1RAB9ACTSBCAPN1ACE | |
| SCHEMBL3292711 | 0.83 | CAPN1 (0.61) | CTSBCAPN1ACE | |
| SCHEMBL2369340 | 0.83 | CAPN1 (0.61) | CTSBCAPN1ACE | |
| SCHEMBL17865652 | 0.83 | CAPN1 (0.61) | CTSBCAPN1ACE | |
| SCHEMBL24444411 | 0.83 | CTSB (0.64) | NPC1RAB9ACTSBCAPN1ACE | |
| SCHEMBL7445998 | 0.83 | CAPN1 (0.55) | NPC1RAB9ACTSBCAPN1ACE | |
| SCHEMBL22204675 | 0.82 | CTSB (0.59) | NPC1RAB9ACTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389176-A1 | NOVEL METABOLIC DISEASE THERAPY | The University Of Sydney (AU) | 2011-11-30 | — | — | EP | claimed |
| US-20110253961-A1 | Combined Guardrail and Cable Safety Systems | TRINITY INDUSTRIES, INC. (US) | 2011-10-20 | — | — | US | claimed |
| WO-2010083570-A1 | NOVEL METABOLIC DISEASE THERAPY | THE UNIVERSITY OF SYDNEY (AU) | 2010-07-29 | — | — | WO | claimed |