SCHEMBL7445998

SCHEMBL7445998

CCNC(=O)N[C@@H](C=O)Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 5/20 0.55
ACE P12821 1/20 0.54
CTSB P07858 5/20 0.53
CTSK P43235 3/20 0.50
CTSL P07711 1/20 0.50
CTSH P09668 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852784 0.83 KMT2A (0.60) CAPN1ACECTSBNPC1RAB9A
SCHEMBL16153848 0.83 CTSB (0.57) CAPN1ACECTSBCTSKCTSL
SCHEMBL1741997 0.83 NPC1 (0.60) CAPN1ACECTSBCTSKCTSL
SCHEMBL2266848 0.82 CAPN1 (0.58) CAPN1ACECTSB
SCHEMBL2269431 0.82 CAPN1 (0.58) CAPN1ACECTSB
SCHEMBL5563236 0.82 CAPN1 (0.58) CAPN1ACECTSB
SCHEMBL2369340 0.82 CAPN1 (0.61) CAPN1ACECTSB
SCHEMBL17865652 0.82 CAPN1 (0.61) CAPN1ACECTSB
SCHEMBL3292711 0.82 CAPN1 (0.61) CAPN1ACECTSB
SCHEMBL26258443 0.81 NPC1 (0.77) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748333-A4 ANTITHROMBOTIC AGENTS LILLY CO ELI (US) 2000-05-10 EP disclosed
EP-0748333-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1996-12-18 EP disclosed
WO-1995023809-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed