Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.67 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | USP5 | P45974 | 1/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.52 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30450105 | 1.00 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL26566648 | 0.94 | KDM4E (0.61) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL26117094 | 0.90 | ATM (0.63) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL11107537 | 0.89 | KDM4E (0.80) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL24224263 | 0.83 | KDM4E (0.71) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL13113221 | 0.82 | NPC1 (0.51) | KDM4ENPC1RAB9ASLC6A9SLC6A5 | |
| SCHEMBL4587114 | 0.82 | NPC1 (0.51) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL833975 | 0.82 | ITGB3 (0.56) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL28484131 | 0.82 | ALDH1A1 (0.73) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL23014282 | 0.82 | ALDH1A1 (0.73) | KDM4EMAPTNPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092074-A1 | Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof | GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) | 2026-04-02 | — | — | US | disclosed |
| EP-4574830-A1 | ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Guangzhou Vinnocent Pharmaceutical Limited (CN) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024061371-A1 | ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州威诺森医药科技有限公司 | 2024-03-28 | — | — | WO | disclosed |
| CN-109071459-B | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof | 米托布里奇公司 | 2022-08-16 | — | — | CN | disclosed |
| US-11358954-B2 | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof | MITOBRIDGE, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| US-11358954-B2 | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof | MITOBRIDGE, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| WO-2021050992-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| EP-3442948-B1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MITOBRIDGE INC (US) | 2020-12-16 | — | — | EP | disclosed |
| EP-3442948-B1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MITOBRIDGE INC (US) | 2020-12-16 | — | — | EP | disclosed |
| US-20200347037-A1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MITOBRIDGE, INC. (US) | 2020-11-05 | — | — | US | disclosed |
| US-8040502-B2 | Optical inspection of flat media using direct image technology | WDI WISE DEVICE INC. (CA) | 2011-10-18 | — | — | US | disclosed |
| WO-2010084979-A1 | BENZODIAZEPIN-2-ON DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-07-29 | — | — | WO | disclosed |
| CN-101500986-A | Di-aryl substituted amides as GLYT1 inhibitors | HOFFMANN LA ROCHE (CH) | 2009-08-05 | — | — | CN | disclosed |
| EP-2066620-A1 | DI-AROMATIC SUBSTITUTED AMIDES AS INHIBITORS FOR GLYT1 | F. Hoffmann-Roche AG (CH) | 2009-06-10 | — | — | EP | disclosed |
| US-20080076806-A1 | Di-aromatic substituted amides as inhibitors for GlyT-1 | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-27 | — | — | US | disclosed |
| WO-2008022938-A1 | DI-AROMATIC SUBSTITUTED AMIDES AS INHIBITORS FOR GLYT1 | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-28 | — | — | WO | disclosed |
| US-4775693-A | Method for controlling insects and acarina with the use of cinnamamide compounds | AMERICAN CYANAMID COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0274546-A1 | New oxazolinone compounds useful as intermediates for the preparation of insecticidal and acaracidal cinnamide compounds | AMERICAN CYANAMID COMPANY (US) | 1988-07-20 | — | — | EP | disclosed |
| US-4727155-A | CINNAMAMIDES | AMERICAN CYANAMID COMPANY (US) | 1988-02-23 | — | — | US | disclosed |
| US-4659857-A | INSECTICIDES AND ACARICIDES EFFECTIVE FOR PROTECTING CORPS; STOMACH AND CONTACT POISONS | AMERICAN CYANAMID COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347037-A1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | PPARG, PPARD, PPARA | KDM4E 3780/4885MAPT 2292/4885HIF1A 1738/4885 |
| US-20080076806-A1 | Di-aromatic substituted amides as inhibitors for GlyT-1 | AGXT, SLC1A2, GRIA1 | KDM4E 2018/4885MAPT 102/4885HIF1A 2539/4885 |
| US-20260092074-A1 | Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof | STS, NR5A1, CYP21A2 | KDM4E 1112/4885MAPT 4813/4885HIF1A 2113/4885 |
| US-11358954-B2 | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof | PPARG, PPARD, PPARA | KDM4E 3780/4885MAPT 2292/4885HIF1A 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.