Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.67 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | USP5 | P45974 | 1/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.52 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742166 | 1.00 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL26566648 | 0.94 | KDM4E (0.61) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL26117094 | 0.90 | ATM (0.63) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL11107537 | 0.89 | KDM4E (0.80) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL24224263 | 0.83 | KDM4E (0.71) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL13113221 | 0.82 | NPC1 (0.51) | KDM4ENPC1RAB9ASLC6A9SLC6A5 | |
| SCHEMBL4587114 | 0.82 | NPC1 (0.51) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL833975 | 0.82 | ITGB3 (0.56) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL28484131 | 0.82 | ALDH1A1 (0.73) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL23014282 | 0.82 | ALDH1A1 (0.73) | KDM4EMAPTNPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204484-B | The method comprises the following steps of 18 F-labeled fluoropyridine formylglycine, and preparation method and application thereof | 山西医科大学第一医院 | 2023-07-21 | — | — | CN | disclosed |