Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | GRK3 | P35626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16511359 | 0.95 | TSHR (0.43) | TSHRMEN1HPGDKMT2AGRM4 | |
| SCHEMBL27333271 | 0.86 | NPC1 (0.44) | TSHRHPGDNPC1SMN1; SMN2RAB9A | |
| SCHEMBL4190714 | 0.80 | KDM4E (0.50) | TSHRMEN1HPGDKMT2ANPC1 | |
| SCHEMBL14884315 | 0.79 | NCF1 (0.42) | TSHRHPGDGRM4NPC1SMN1; SMN2 | |
| SCHEMBL29469520 | 0.77 | MEN1 (0.41) | TSHRMEN1HPGDKMT2ANPC1 | |
| SCHEMBL22190243 | 0.77 | APP (0.44) | HPGDNPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL28074874 | 0.77 | NPC1 (0.42) | TSHRHPGDNPC1SMN1; SMN2RAB9A | |
| SCHEMBL22190232 | 0.77 | MEN1 (0.41) | TSHRMEN1HPGDKMT2ANPC1 | |
| SCHEMBL15911434 | 0.76 | NPC1 (0.43) | TSHRHPGDGRM2NPC1SMN1; SMN2 | |
| SCHEMBL9266875 | 0.75 | LTA4H (0.43) | HPGDKMT2AGRM2NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009830-A1 | SUPPORTED POLYOLEFIN CATALYST AND PREPARATION AND APPLICATION THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2016-01-14 | — | — | US | disclosed |